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Artificial Intelligence
arXiv (cs.AI) · July 16, 2026

Parameter-efficient Prompt Tuning of Vision Foundation Model With Adaptive Focal Loss for Interpretable MCI Screening

Javad Khoramdel, Farhad Hoseyni, Amirhossein Nikoofard

Mild cognitive impairment often shows up before Alzheimer's, and one cheap way to screen for it is in how patients perform simple drawing tests. Automating that reading is hard: little data, lopsided classes, and the tricky cases sitting right on the diagnostic fence. Prior systems threw large fine-tuned models at it and bolted explanations on afterward.

This paper keeps the big DINOv2 vision model frozen and trains just three task-specific prompt tokens, about 1.19 million parameters. Each token queries the image through a shared cross-attention layer, so the attention maps are the explanation, built in rather than reconstructed. A modified focal loss folds continuous MoCA cognitive scores into training to handle the borderline cases. Across five-fold cross-validation it reaches an MCI-class F1 of 0.641 and AUC of 0.795, beating a heavier ResViT baseline by 0.110 in F1.

Those numbers are honest about how hard borderline MCI is, so read the paper for the full setup.

From the arXiv (cs.AI) abstract

Mild Cognitive Impairment is a critical early stage of cognitive decline that frequently precedes Alzheimer's disease, yet its automated detection from neuropsychological drawing tests remains fundamentally constrained by data scarcity, class imbalance, and diagnostic ambiguity near clinical boundaries. Existing methodologies attempt to bypass these constraints using computationally expensive, fully fine-tuned hybrid architectures that relegate spatial explainability to a…


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